Answering Your Questions About COVID-19, Long-COVID, and Staying Healthy During Cold and Flu Season

With the onset of RSV, cold and flu season, and the persistence of COVID-19, it's important to learn from the past to understand how we can prevent and limit the impact of our exposure to these challenging viral illnesses. In today’s episode of my series I’m calling Health Bites, I am tackling a topic that has left an indelible mark on the world: the COVID-19 pandemic. As we navigate through new variants and climbing cases, it's crucial to unravel the reasons why so many Americans got so sick and died during the pandemic. We dig into the questions of why we as a nation were so susceptible to COVID-19’s deadly effects. I also explore why and how Functional Medicine steps in where conventional approaches stumble. This episode is brought to you by AG1, Rupa Health, and Seed. Get your daily serving of vitamins, minerals, adaptogens, and more with AG1. Head to and get 10 FREE travel packs and a FREE Welcome Kit with your first order. Streamline your lab orders with Rupa Health. Access more than 3,000 specialty lab tests and register for a FREE live demo at Seed is offering my community 25% off to try DS-01® for themselves. Visit and use code HYMAN25 for 25% off your first month of Seed's DS-01® Daily Synbiotic.

Supplement Stack to Support Your Immune System During Cold and Flu Season

  • Multivitamin / Multimineral Supplement
  • Vitamin C: 1,000 mg (liposomal)
  • Vitamin D3: 1,000 - 4,000 IU/day with food
  • Zinc citrate: 20 mg/day
  • Omega-3: 2 g/day
  • Quercetin 500mg twice a day with food (mentioned in this episode: HTB Rejuvenate)
  • Melatonin: 1-2mg at night, sustained release
  • Probiotics: MegaSporebiotic: a blend of 5 Bacillus Spores that have been clinically shown to maintain healthy gut barrier function and overall immunity
  • Colostrum: ARMRA Colostrum
  • Peptides:
  • Thymosin Alpha 1
    • 1.5-10 mg/day, depending on severity of acute COVID
    • As symptoms resolve, decrease dose over 3-5 days
    • Dose every 3-4 hours subcutaneously
    • Can take up to 5 mg TA1 IV per day supported with subcutaneous shots for severe disease
    • Consider therapy for 20-30 days
  • Thymosin Beta 4
    • 1.5-10 mg/day, depending on the severity of acute COVID
    • If using high dose with TA1 use low dose TB4 (1.5 mg with TB4 and vice versa)
    • Dose every 3-4 hours subcutaneously
    • Take for the first 10 days and wean as symptoms resolve
  • Thymosin Beta 4 fragment 1-4
    • 2-5 mg/day
  • BPC 157
    • 500 mcg to 1 mg twice a day
  • LL 37
    • 100 mcg twice a day during acute period of 10 days, then decrease too 100 mcg/day for 10 days
  • Bioregulator Peptides orally and subcutaneously
Supplements for ACE2 Enhancement
  • Vitamin D: 2,000 - 6,000 IU/day with food
  • Quercetin: 500mg twice a day
  • Curcumin: 500 - 1,000 mg/day
  • Omega-3: 2g/day
  • CBD: 150 mg/day
  • Resveratrol: 200 to 1200 mg/day
  • Alpha Lipoic Acid: 300 mg twice a day with food
  • NAC: 600-1200 mg two to three times a day
Supplements for Mitochondrial Health
  • CoQ10 (ubiquinol): beneficial for reversing COVID-related fatigue 100 mg 2-3x/day
  • Acetyl-L-carnitine
  • Methylated B vitamins
  • Urolithin A: pomegranates (or supplement: MitoPure)
Supplements for Post-Infection / Early Treatment / Immune Support Most Important:
  • Quercetin: 500 mg twice a day by Pure Encapsulations (1000 mg twice a day if sick)
  • Vitamin D3: 5000 IU/dayday by Pure Encapsulations (50,000 IU/day if sick for 10 days)
  • Zinc citrate: 30 mg twice a day by Pure Encapsulations
  • Vitamin C: 4,000 mg twice a day if sick
  • NAC: 600 mg twice a day (or Liposomal Glutathione by Quicksilver 4 pumps twice a day)
  • Curcumin: 1000 mg twice a day (Meriva by Thorne)
  • NAD+: 4 pumps twice a day by Quicksilver
Additional Support:
  • Vitamin A: 5000 IU/ day or more 10,000 or 20,000 IU for a week by Pure Encapsulations
  • ECG: 500 mg twice a day by Pure Encapsulations
  • Selenium: 200 mcg/day by Pure Encapsulations
  • Melatonin: 3-20 mg at night by Pure Encapsulations
  • NAC (n-acetylcysteine): 600 mg twice a day
  • Alpha-Lipoic acid:100 mg twice a day
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