GABA (gamma-aminobutyric acid) is an amino acid produced in the human body that functions as the principle inhibitory neurotransmitter in the central nervous system. GABA is associated with the parasympathetic side of the autonomic nervous system which balances the sympathetic (fight-or-flight) side. Many pharmacological agents exert anxiolytic, analgesic, anticonvulsant and sedative effects by modulating GABA receptor activity, or blocking the reuptake of GABA, thus increasing GABA activity.
Many toxins, such as mercury, and some physical traumas, such as head trauma, elicit neurotoxic effects though glutamate receptors in the brain (called NMDA-mediated neurotoxicity). This produces a feedback loop of inflammation,neurotoxicity, and anxiety. GABA supplementation can help break that loop by building the pool of GABA.
Use of powdered GABA is not efficient because it is poorly absorbed and does not easily cross the blood-brain barrier. Studies have shown that GABA administered with phosphatidylserine improved GABA’s activity and was proposed to be due to an increased ability to cross the blood-brain barrier.
L-Theanine is an amino acid found naturally in tea. Research suggests that theanine affects inhibitory neurotransmission (parasympathetic) and has been shown to have relaxing effectson cognitive thinking and blood pressure.
GABA has also shown useful before taking detoxification products to dampen negative responses.
Ingredients and Recommended Use
Take 4 pumps whenever needed, especially before bed. Take 2 pumps at a time directly by mouth, hold 30 seconds and then swallow.